EPS8.06 Prevalence of hypoglycaemia, measured by flash glucose monitoring, after moderate intensity aerobic exercise in adults with cystic fibrosis, compared to healthy controls

Objectives: People with or without Cystic Fibrosis-Related Diabetes (CFRD) have increased prevalence of hypoglycaemia, related to insulin therapy and reactive hypoglycaemia. type 1 2 diabetes mellitus are at risk hypoglycaemia within 48hr after exercise, however this has not been objectively measured in people CF. We aimed investigate the using flash glucose monitoring, moderate intensity aerobic exercise adults CF compared healthy controls. Methods: Adults controls were recruited complete a 20-minute supervised, cycling session wear continuous sensor for 10 days. The was defined as number participants percentage time levels <3.9 mmol/L exercise. Results: 15 (mean age 37 ± 14 years, FEV1 82 17%, BMI 24.3 3.2, 7 abnormal tolerance (impaired tolerance, n = 2, CFRD, 5)) 36 100 11%, 24.9 4.3) completed study. There no significant differences between control groups (40% v 33% respectively; median 0.0% both groups). Compared normal however, those had significantly higher (71% 25%, p < 0.05) longer (median 0.5% 0.0%, 0.05). Among who experienced there difference nadir (average 3.4 Conclusions: Post-exercise is more prevalent though episodes mostly mild brief. These should be advised monitor it does appear risk.